Research and Work Experience

Read about the research groups I’ve been a part of below, organized from most to least recent. To learn more about my current research interests, check out this link.


hyperfine

MRI Sequence Development Team, Hyperfine

During the spring and summer of 2021, I worked as a software engineering intern in the MRI Image Reconstruction Group at Hyperfine, a startup based in Guilford, CT that builds low-field, portable MRI machines. I wrote scripts to visualize and analyze batches of imaging data, and optimized algorithms for both motion correction for DWI imaging and spike noise correction for FSE sequences.



shapiro-lab

Mikhail Shapiro Lab, Caltech

I worked on engineering probiotic bacteria and CAR T's to be thermally actuated using focused ultrasound to spatially localize immuntherapeutic activity. I also manipulated celular water diffusivity to act as a sensor for hypoxia in MRI imaging. I was an undergraduate research fellow in this lab from September 2017 until March 2021, the entire time I was at Caltech. You can read more about the specifics of my research here.



gruenert-lab

Dieter Gruenert Lab, UCSF

During high school, I spent two years studying differentiation of iPSCs to ultimately treat hypoparathyroidism using regenerative medicine. I also worked on developing gene therapies for cystic fibrosis through correcting W1282X and $\Delta$F508 genetic mutations using CRISPR-Cas9. I was a research intern in this lab from June 2015 until July 2017. I was recognized with honorable mention honors in the national 2017 Regeneron Science Competition for my research.



Publications, Presentations, and Manuscripts

  1. Abedi MA$^{\dagger}$, Yao M$^{\dagger}$, Mittelstein DR, Bar-Zion A, Swift M, Lee-Gosselin A, Shapiro M. (2020). Thermal bioswitches for localized activation of microbial immunotherapies. (Currently under peer review, preprint here, $^{\dagger}$Equal contribution)
  2. Immunotherapy: Clinical: Underlying Mechanisms and Clinical Applications. (2020 Oc 25). Caltech Medlife Tech in Medicine Seminar Series. (Invited, Recording)
  3. Thermal Bioswitches for Localized Activation of Microbes. (2020 Oct 15). Presented at 2020 Biomedical Engineering Society (BMES) Virtual Meeting
  4. Yao M, Uhr L, Daghlian G, Amrute JM, Deshpande R, Mathews B, Patel SA, Henri R, Liu G, Reierson K, Johnson G. (2020). Demonstration of a longitudinal medical education model (LMEM) to teach point-of-care ultrasound in resource-limited settings (Published in POCUS Journal)
  5. Maw AM, Galvin B, Henri R, Yao M, Exame B, Fleshner M, Fort MP, Morris MA. (2019). Stakeholder perceptions of point-of-care ultrasound implementation in resource-limited settings (Published in Diagnostics)

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